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Depends some people, for reasons that are not clear, are more sensitive to changes in serotonergic medications such as paroxetine paxil and suffer from discontinuation symptoms.

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Risk of mydriasismay trigger angle closure attack in patients with angle closure glaucoma with anatomically narrow angles without a patent iridectomy.

Patients should be monitored closely for changes in behaviorclinical worseningand suicidal tendenciesthis should be done during the initial 1-2 months of therapy and dosage adjustments.

Some young people have thoughts about suicide when first taking an antidepressantYour doctor should check your progress at regular visitsYour family or other caregivers should also be alert to changes in your mood or symptoms.

Do not use an MAO inhibitor within 14 days before or 14 days after you take paroxetineA dangerous drug interaction could occurMAO inhibitors include isocarboxazidlinezolidphenelzinerasagilineselegilineand tranylcypromineAfter you stop taking paroxetine you must wait at least 14 days before you start taking an MAO inhibitor.

XDo not use in pregnancyRisks involved outweigh potential benefitsSafer alternatives exist.

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123 i-adam spect was used to investigate the sertocc induced by paroxetine in major depression disorder mdd patients, to compare the sert availability in drug-free mdd patients and healthy volunteers, and to study the relationship between paroxetine plasma concentrations cp and sertocc.

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